When I think of comforting, flavorful meals, Beef Gyros always come to mind! There’s something so satisfying about sinking your teeth into a warm pita stuffed with tender, juicy beef and all those fresh toppings. What makes this dish even better is the versatility of cooking it in either a Slow Cooker or an Instant Pot. With the Slow Cooker, you can set it and forget it, letting those spices mingle as the beef slowly transforms into the most tender bite you can imagine. Trust me, the aroma that fills your kitchen is simply irresistible!

If you’re in a hurry, the Instant Pot is your best friend. In just 45 minutes, you can have those same delicious, tender gyros ready to enjoy. I love how both methods bring out the rich flavors of the spices and the beef, making it easy to cater to my busy schedule without sacrificing taste. Plus, this recipe is perfect for gatherings—everyone can customize their gyros with fresh veggies and tzatziki sauce, making each bite feel special. I can’t wait for you to try this recipe and experience the joy of Beef Gyros in your own home!
Ingredients for Beef Gyros
Gathering the right ingredients is key to making the most delicious Beef Gyros! Here’s what you’ll need:
- 3 pounds beef chuck roast, sliced into thin ¼-inch strips
- ¾ teaspoon salt
- ½ teaspoon freshly ground black pepper
- 3 Tablespoons olive oil
- 2½ teaspoons garlic powder
- 2 teaspoons dried oregano
- 1 teaspoon ground cumin
- 1 teaspoon dried thyme
- 2 Tablespoons fresh lemon juice
- 5 soft pitas
- 5 lettuce leaves
- 1 cup cherry tomatoes, halved
- ¼ red onion, thinly sliced
- 1 English cucumber, sliced and halved
- 1 cup plain Greek yogurt
- 1 clove garlic, finely minced
- 1 Tablespoon fresh lemon juice
- 1 Tablespoon olive oil
- 1 teaspoon red wine vinegar
- 1 teaspoon dried dill weed
- Salt and freshly ground black pepper, to taste
These ingredients come together to create a flavor explosion that will have everyone asking for seconds! Make sure to grab fresh toppings to give your gyros that extra zing!
How to Prepare Beef Gyros
Preparing Beef Gyros is easier than you might think, and I promise you’ll be rewarded with an incredible meal that will impress everyone at the table! Let’s dive into how to make these delicious gyros, starting with the tzatziki sauce because it’s a game-changer for flavor!
Preparing the Tzatziki Sauce
First things first, let’s whip up that tzatziki sauce. In a mixing bowl, combine 1 cup of plain Greek yogurt, 1 clove of finely minced garlic, 1 tablespoon of fresh lemon juice, and 1 tablespoon of olive oil. Then, add in 1 teaspoon of red wine vinegar and 1 teaspoon of dried dill weed. Don’t forget to sprinkle in salt and pepper to taste!
Mix everything together until it’s smooth and creamy. Once combined, cover the bowl and refrigerate it for at least 30 minutes, or even longer if you have time. This step is super important because it allows the flavors to meld beautifully, creating that tangy, refreshing taste that pairs perfectly with your gyros!
Slow Cooker Method for Beef Gyros
Now, let’s get to the star of the show—the beef! Start by trimming any large pieces of fat off your 3 pounds of beef chuck roast. Slice it into thin ¼-inch strips. This helps the beef cook evenly and absorb all those yummy spices.
Place the sliced beef in the bottom of your slow cooker. In a small bowl, mix together 3 tablespoons of olive oil, 2½ teaspoons of garlic powder, 2 teaspoons of dried oregano, 1 teaspoon of ground cumin, 1 teaspoon of dried thyme, and the juice of 2 tablespoons of fresh lemon juice. Sprinkle in ¾ teaspoon salt and ½ teaspoon freshly ground black pepper, and stir everything together until well combined.
Pour this heavenly seasoning mix over the beef, making sure each piece is coated. Cover your slow cooker and set it to LOW for about 6 hours. Trust me, you’ll know it’s done when the beef is fork-tender and just falls apart! Before serving, taste and adjust the seasoning if needed—it’s your dish, after all!
Instant Pot Method for Beef Gyros
If you’re short on time, the Instant Pot is a lifesaver! Follow the same steps for trimming and slicing the beef. Place the strips in the Instant Pot and mix up the seasoning just like before, but this time, add ⅓ cup of water to the mixture. Pour it over the beef and give it a little stir.
Close the lid, set the valve to “sealing,” and cook on Manual/High Pressure for 30 minutes. Once the cooking time is up, allow it to rest for 15 minutes before releasing the pressure carefully. Just like the slow cooker, ensure the beef is tender and adjust the flavors if needed.
Whichever method you choose, you’ll end up with beef that’s bursting with flavor and so tender it’s practically melting in your mouth. Now, let’s move on to assembling these delicious gyros!
Nutritional Information
When you’re enjoying these Beef Gyros, it’s good to know what you’re putting into your body! Here’s an estimated breakdown of the nutritional values per serving (1 gyro):
- Calories: 798 kcal
- Fat: 44 g
- Saturated Fat: 15 g
- Unsaturated Fat: 28 g
- Trans Fat: 2 g
- Carbohydrates: 40 g
- Fiber: 3 g
- Sugar: 4 g
- Protein: 63 g
- Cholesterol: 190 mg
- Sodium: 898 mg
Keep in mind that these values are approximate and can vary based on the specific brands of ingredients you use and any modifications you make. But rest assured, you’re digging into a balanced meal packed with protein and flavor! Enjoy every bite knowing you’re treating yourself to something delicious and satisfying!
FAQ about Beef Gyros
Q1: Can I use a different cut of beef for this recipe?
Absolutely! While I love using beef chuck roast for its tenderness and flavor, you can also try flank steak or sirloin. Just remember that cooking times may vary slightly depending on the cut you choose, so keep an eye on it!
Q2: What can I substitute for Greek yogurt in the tzatziki sauce?
If you don’t have Greek yogurt on hand, you can use regular plain yogurt or even sour cream. Just keep in mind that the texture and flavor might change a bit. If you’re looking for a lighter option, try using unsweetened coconut yogurt for a dairy-free version!
Q3: How can I make these Beef Gyros spicier?
If you enjoy a kick, try adding red pepper flakes or cayenne pepper to the seasoning mix. You can also add some sliced jalapeños or a drizzle of hot sauce when assembling your gyros. Spice it up to match your taste!
Q4: Can I prepare the Beef Gyros in advance?
Definitely! You can marinate the beef in the seasoning overnight for even more flavor. Just cook it the next day as directed. Also, you can make the tzatziki sauce ahead of time and store it in the fridge, so everything’s ready to go when you are!
Q5: What are some good side dishes to serve with Beef Gyros?
I love pairing my Beef Gyros with a simple Greek salad or roasted vegetables. You could also serve some crispy fries or even homemade potato wedges for a fun twist. And don’t forget some extra tzatziki on the side for dipping—yum!
Why You’ll Love This Recipe
- Quick and Easy: Whether you choose the Slow Cooker or Instant Pot, this recipe is a breeze to prepare. Just set it and let it do its magic—perfect for busy weeknights!
- Flavor Explosion: The combination of spices and tender beef creates a mouthwatering experience that will have everyone at the table raving about the flavors!
- Customizable: Beef Gyros are super versatile! You can load them up with your favorite toppings, from fresh veggies to tangy tzatziki, making each gyro uniquely yours.
- Perfect for Any Occasion: Whether it’s a casual dinner, a family gathering, or a fun party, these gyros are a hit with friends and family alike. They’re sure to impress!
- Leftover Friendly: If you happen to have any leftovers, they’re just as delicious the next day! Use them in salads, wraps, or even on their own for a quick meal.

Tips for Success
Getting your Beef Gyros just right is all about a few simple tips and tricks! Trust me, these little details will make a huge difference in flavor and texture.
Properly Slice the Beef
When it comes to slicing your beef chuck roast, aim for thin ¼-inch strips. This not only helps the meat cook evenly but also ensures each bite is tender and full of flavor. I recommend slicing against the grain for maximum tenderness—this makes a world of difference! If the roast is a bit tough to handle, pop it in the freezer for about 30 minutes before slicing; it firms up nicely and makes cutting a breeze.
Adjusting Flavors in the Tzatziki Sauce
Your tzatziki sauce is where you can really make it your own! If you like a bit more zing, don’t hesitate to add a touch more lemon juice or a pinch of salt. Also, if you’re a dill lover like me, feel free to double the dill weed for an extra herby kick. And if you want a creamier texture, you can always stir in a little more yogurt to suit your taste!
Marinate for Maximum Flavor
If you have the time, let your sliced beef marinate in the seasoning mix for a few hours—ideally overnight. This will deepen the flavor and make the meat even more tender. Just remember to keep it covered in the fridge while it’s marinating!
Serving Suggestions
When it’s time to assemble your gyros, don’t hold back on the toppings! Fresh veggies like lettuce, tomatoes, and cucumbers add that crunchy freshness that pairs perfectly with the savory beef. And when it comes to tzatziki, a generous dollop is a must! You can even add a sprinkle of feta cheese or a few olives for an authentic Mediterranean touch.
Storing Leftovers
If you happen to have any leftovers, store the beef and toppings separately to keep everything fresh. You can reheat the beef gently on the stove or in the microwave. Just be careful not to overcook it again; you want to keep that juicy goodness! Enjoy your Beef Gyros as a quick lunch or dinner the next day—they’re just as delicious!
With these tips in mind, you’re on your way to making the most amazing Beef Gyros that will wow your family and friends. Happy cooking!
Storage & Reheating Instructions
Storing your Beef Gyros properly is essential to keep that delicious flavor intact for the next day. After enjoying your meal, let any leftovers cool down to room temperature before storing them. I recommend keeping the beef and toppings separate to maintain freshness. You can store the beef in an airtight container in the fridge for up to 3 days. Just make sure it’s well-sealed to avoid any unwanted odors from your fridge!
As for the fresh toppings, like the lettuce, tomatoes, and cucumbers, keep them in a separate container. They tend to get soggy if mixed with the beef, and nobody wants a wilted gyro! You can store the tzatziki sauce in its own container as well—just be sure to give it a good stir before serving again.
When it’s time to enjoy your leftovers, reheating the beef is a breeze. I like to gently warm it up on the stovetop over medium heat, stirring occasionally to ensure even heating. This method helps retain its juiciness. If you’re short on time, you can also use the microwave, but do so in short bursts to avoid drying it out. Heat in 30-second intervals, checking often until it’s warmed through.
Once the beef is heated, simply reassemble your gyros with the fresh toppings and a dollop of tzatziki sauce, and voila! You’re ready to dive back into those flavorful Beef Gyros without losing an ounce of deliciousness. Enjoy every bite, just like the first time!
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Beef Gyros (Slow Cooker or Instant Pot): 5 Irresistible Tips
- Total Time: 6 hours 30 minutes (Slow Cooker) or 1 hour 15 minutes (Instant Pot)
- Yield: 5 servings 1x
- Diet: Gluten Free
Description
Slow-cooked or Instant Pot Beef Gyros served with fresh toppings and tzatziki sauce.
Ingredients
- 3 pounds beef chuck roast, sliced into thin ¼-inch strips
- ¾ teaspoon salt
- ½ teaspoon freshly ground black pepper
- 3 Tablespoons olive oil
- 2½ teaspoons garlic powder
- 2 teaspoons dried oregano
- 1 teaspoon ground cumin
- 1 teaspoon dried thyme
- 2 Tablespoons fresh lemon juice
- 5 soft pitas
- 5 lettuce leaves
- 1 cup cherry tomatoes, halved
- ¼ red onion, thinly sliced
- 1 English cucumber, sliced and halved
- 1 cup plain Greek yogurt
- 1 clove garlic, finely minced
- 1 Tablespoon fresh lemon juice
- 1 Tablespoon olive oil
- 1 teaspoon red wine vinegar
- 1 teaspoon dried dill weed
- Salt and freshly ground black pepper, to taste
Instructions
- Combine all tzatziki sauce ingredients in a bowl.
- Stir well and refrigerate until ready to serve.
- Trim large pieces of fat from the beef roast and slice into thin ¼-inch strips.
- Place beef in the bottom of the slow cooker.
- Mix olive oil, garlic powder, oregano, cumin, thyme, lemon juice, salt, and pepper in a small bowl. Pour over beef.
- Cover and cook on LOW for 6 hours or until beef is tender.
- Assemble gyros: Place a lettuce leaf on each pita. Top with beef, tomatoes, cucumber, onion, and tzatziki sauce.
- For Instant Pot, trim and slice beef as above, and place in the Instant Pot.
- Mix ⅓ cup water, olive oil, garlic powder, oregano, cumin, thyme, lemon juice, salt, and pepper in a small bowl. Pour over beef.
- Cover, set the valve to “sealing,” and cook on Manual/High Pressure for 30 minutes.
- Allow to rest for 15 minutes before releasing pressure. Taste and adjust seasoning if needed.
- Assemble gyros as above.
Notes
- Tzatziki sauce and all vegetables can be prepared in advance and stored separately in the fridge.
- Beef can be frozen before or after cooking. For best results, freeze thinly sliced beef in a freezer-safe bag with the marinade. Thaw completely in the fridge before cooking.
- Prep Time: 30 minutes
- Cook Time: 6 hours (Slow Cooker) or 45 minutes (Instant Pot)
- Category: Main Dish
- Method: Slow Cooker or Instant Pot
- Cuisine: Mediterranean
Nutrition
- Serving Size: 1 gyro
- Calories: 798 kcal
- Sugar: 4 g
- Sodium: 898 mg
- Fat: 44 g
- Saturated Fat: 15 g
- Unsaturated Fat: 28 g
- Trans Fat: 2 g
- Carbohydrates: 40 g
- Fiber: 3 g
- Protein: 63 g
- Cholesterol: 190 mg
Keywords: Beef Gyros, Slow Cooker, Instant Pot, Tzatziki Sauce