Let me tell you about my absolute favorite comfort food: Cattle Drive Casserole. This dish is a warm hug on a plate, packed with layers of savory beef, vibrant veggies, and gooey cheese that melt together to create a hearty meal everyone loves. I remember making this casserole with my mom on chilly Sunday afternoons, filling our home with the most inviting aromas. It always brought the family together, whether we were gathered for a casual dinner or a big holiday feast. There’s something so special about tucking into a dish that feels like home, and this casserole does just that. It’s easy to prepare, making it perfect for busy weeknights or lazy weekends. Trust me, once you try this Cattle Drive Casserole, you’ll want to keep it in your recipes for years to come. The best part? It’s even better as leftovers!

Ingredients List
Here’s everything you’ll need to whip up this delicious Cattle Drive Casserole. Gather these ingredients before you start, and you’ll be on your way to a comforting meal in no time!
- 1.5 pounds Lean Ground Beef
- 1 Red Bell Pepper, seeded and chopped
- 1 Yellow Onion, chopped
- 1 ounce Taco Seasoning Mix
- 2 ½ cups Biscuit Mix, like Bisquick
- 1 cup Water
- Cooking Spray, like Pam
- ½ cup Sour Cream
- ½ cup Mayonnaise
- 4 ounces Diced Green Chiles, drained
- 1 ½ cups Cheddar Cheese, Fiesta Blend, shredded, divided
- 1 teaspoon Garlic Powder
- ½ cup Salsa, mild
How to Prepare Cattle Drive Casserole
Get ready to create a mouthwatering Cattle Drive Casserole! Follow these simple steps, and you’ll have a comforting meal that’s sure to impress. Let’s dive in!
Step 1: Preheat the Oven
First things first, you’ll want to preheat your oven to 350℉. Preheating is crucial because it ensures your casserole bakes evenly and gets that perfect golden crust!
Step 2: Cook the Ground Beef
Next, heat a skillet over medium-high heat and add in the 1.5 pounds of lean ground beef. Use a spoon to break it apart as it cooks, stirring occasionally until there’s no pink left. Once it’s browned, drain any excess fat to keep the casserole from being greasy. Trust me, this step makes a big difference!
Step 3: Prepare the Biscuit Dough
In a mixing bowl, combine 2 ½ cups of biscuit mix and 1 cup of water. Stir it together until it’s well mixed – you want it to be nice and smooth! After that, spray a casserole dish with cooking spray and press the dough into the bottom of the dish. Pop it in the preheated oven for about 5-8 minutes, just until it’s set and lightly golden. This creates a solid base for all those delicious layers!
Step 4: Cook the Vegetables
Now, let’s add some flavor! Toss in the chopped 1 yellow onion and 1 red bell pepper to the cooked ground beef. Stir it all together and cook for about 4 minutes until the veggies are tender but still have a bit of crunch. This adds a lovely texture and sweetness to your casserole!
Step 5: Assemble the Layers
Spread the cooked beef and vegetable mixture evenly over the baked biscuit layer. Make sure every bite has a taste of that savory goodness. It’s starting to come together!
Step 6: Prepare the Sour Cream Layer
In a separate bowl, mix together ½ cup sour cream, ½ cup mayonnaise, 4 ounces of drained diced green chiles, ¾ cup of shredded cheddar cheese, and 1 teaspoon of garlic powder. Mix until it’s smooth and creamy. This layer adds richness and a wonderful flavor that complements the beef perfectly!
Step 7: Add Salsa and Cheese
Now for the fun part! Dollop small spoonfuls of ½ cup mild salsa over the sour cream layer and then sprinkle the remaining shredded cheese evenly on top. You’ll want to make sure it’s nicely covered for that gooey, cheesy finish!
Step 8: Bake the Casserole
Finally, place your casserole back in the oven, uncovered, and let it bake for about 30 minutes. You’ll know it’s ready when it’s hot and bubbly all around the edges. Oh, that smell will have everyone rushing to the table!
Why You’ll Love This Recipe
This Cattle Drive Casserole is more than just a meal; it’s a true comfort food that brings everyone together. Here are a few reasons why you’ll adore it:
- Hearty and Filling: Packed with layers of beef, veggies, and cheese, it satisfies even the hungriest of appetites.
- Easy to Prepare: With straightforward steps and minimal prep time, it’s perfect for busy weeknights.
- Family-Friendly: Kids and adults alike love the cheesy, flavorful layers; it’s a sure hit at any table.
- Great for Leftovers: This casserole tastes even better the next day, making it ideal for meal prep or potlucks.
Tips for Success
To ensure your Cattle Drive Casserole turns out perfectly every time, here are some tried-and-true tips:
- Don’t Rush the Browning: Make sure the ground beef is nicely browned before adding the veggies. This step enhances the flavor!
- Watch the Biscuit Dough: Keep an eye on the biscuit base while it bakes. You want it set and lightly golden, not overcooked.
- Layer Evenly: Spread each layer evenly in the casserole dish to ensure every bite gets that delicious mix of flavors.
- Let it Cool: Allow the casserole to cool for a few minutes before serving. This helps the layers set, making it easier to cut and serve.
Storage & Reheating Instructions
Storing leftovers of your Cattle Drive Casserole is simple! Just let it cool completely, then cover it tightly with plastic wrap or transfer it to an airtight container. It’ll keep well in the refrigerator for up to 3-4 days. For longer storage, you can freeze it for up to 2 months. When you’re ready to enjoy it again, thaw it in the fridge overnight if frozen. To reheat, pop it in the oven at 350℉ for about 20-25 minutes until it’s heated through. If you’re in a hurry, microwaving individual portions works too—just be sure to cover them to keep the moisture in!
FAQ Section
Got questions about the Cattle Drive Casserole? Don’t worry; I’ve got you covered! Here are some common inquiries that pop up:
- Can I use ground turkey instead of beef? Absolutely! Ground turkey is a great lighter option that works well in this casserole. Just make sure to season it well.
- What can I substitute for the biscuit mix? If you don’t have biscuit mix on hand, you can make your own by combining flour, baking powder, and a pinch of salt. It’ll do the trick!
- Can I add more veggies? Yes! Feel free to toss in some corn, black beans, or even spinach for extra flavor and nutrition.
- How can I spice it up? If you like a little heat, add some jalapeños or use a spicy salsa instead of mild. It’ll give your casserole a nice kick!
- What’s the best way to serve this casserole? It’s delicious on its own, but I love serving it with a side of fresh salad or some warm tortillas to soak up all that cheesy goodness!
Nutritional Information Section
When it comes to enjoying your Cattle Drive Casserole, knowing the nutritional details can help you make informed choices. Keep in mind that nutrition can vary based on the specific ingredients and brands used. Here’s a general breakdown per serving:
- Calories: 400
- Fat: 25g
- Saturated Fat: 10g
- Cholesterol: 70mg
- Sodium: 800mg
- Carbohydrates: 30g
- Fiber: 2g
- Protein: 20g
- Sugar: 3g
This hearty casserole is not only filling but also packs a good balance of protein and fat to keep you satisfied!
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Cattle Drive Casserole: 7 Layers of Comforting Delight
- Total Time: 60 minutes
- Yield: 8 servings 1x
- Diet: Comfort Food
Description
A hearty and flavorful casserole with layers of beef, vegetables, and cheese.
Ingredients
- 1.5 pounds Lean Ground Beef
- 1 Red Bell Pepper, seeded, chopped
- 1 Yellow Onion, chopped
- 1 ounce Taco Seasoning Mix
- 2 ½ cups Biscuit Mix, like Bisquick
- 1 cup Water
- Cooking Spray, like Pam
- ½ cup Sour Cream
- ½ cup Mayonnaise
- 4 ounces Diced Green Chiles, drained
- 1 ½ cups Cheddar Cheese, Fiesta Blend, shredded, divided
- 1 teaspoon Garlic Powder
- ½ cup Salsa, mild
Instructions
- Preheat the Oven: Set the oven to 350℉.
- Cook the Ground Beef: Heat a skillet over medium-high heat. Add the ground beef and break it apart with a spoon. Cook until no longer pink, stirring occasionally. Drain off any excess fat.
- Prepare the Biscuit Dough: In a mixing bowl, combine the biscuit mix and water. Stir until well mixed. Spray a casserole dish with cooking spray and press the dough into the dish. Bake in the preheated oven for 5-8 minutes, or until the dough is set and lightly golden.
- Cook the Vegetables: Add chopped onions and red bell pepper to the cooked ground beef. Stir and cook for about 4 minutes. Add taco seasoning and mix well. Remove from heat.
- Assemble the Layers: Spread the cooked ground beef mixture evenly on top of the baked biscuit layer.
- Prepare the Sour Cream Layer: In a medium bowl, combine sour cream, mayonnaise, drained green chiles, ¾ cup shredded cheese, and garlic powder. Mix until smooth. Spread this mixture over the ground beef layer.
- Add Salsa and Cheese: Add small spoonfuls of salsa over the sour cream layer. Sprinkle the remaining shredded cheese evenly on top.
- Bake: Place the casserole back in the oven, uncovered, and bake for 30 minutes or until hot and bubbly.
Notes
- Let the casserole cool for a few minutes before serving.
- Can substitute ground turkey for a lighter option.
- Prep Time: 20 minutes
- Cook Time: 40 minutes
- Category: Casserole
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 slice
- Calories: 400
- Sugar: 3g
- Sodium: 800mg
- Fat: 25g
- Saturated Fat: 10g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 30g
- Fiber: 2g
- Protein: 20g
- Cholesterol: 70mg
Keywords: Cattle Drive Casserole, casserole, beef, easy recipe